For each macaque gene, we provided a Gene Page here to illustrate detailed functional annotations in different categories, such as gene information, expression profile, regulation, variation and repeats, phenotypes and disease, function, as well as drug development.

Summary
Entrez ID: 706614 (Human: 6749)
Offical Symbol: SSRP1 (Human: SSRP1)
Strand: +
Location: chr14:16084045-16094185
Gene Biotype: protein-coding
Full Name: structure specific recognition protein 1
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Alias: N.A.
RefSeq: (NW_001100366.1, XM_001103334.2, XP_001103334.1) (NC_007871.1, XM_001103334.2, XP_001103334.1) (-, NM_001257891.1, NP_001244820.1)
Ensembl: (ENSMMUG00000017810, ENSMMUT00000025029, ENSMMUP00000023416)
UniGene: Mmu.4565
UniProt: F7E0V3 (F7E0V3_MACMU)
Publications: 22002653
Wiki: Wikipedia, WikiGenes, GeneCard
RefSeq Summary:

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## Transcript_exon_combination_evidence :: M86737.1 [ECO:0000332] ##RefSeq-Attributes-END## Refer to NM_003146.

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Structure
RefSeq
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RNA(1)
>gi|383872504|ref|NM_001257891.1| Macaca mulatta structure specific recognition protein 1 (SSRP1), mRNA2737nt Get Sequence
[+]
Protein(1)
>gi|383872505|ref|NP_001244820.1| FACT complex subunit SSRP1 [Macaca mulatta]709AA Get Sequence
[+]
Ensembl
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RNA(1)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT000000250292597nt
[+]
RhesusBase2 Gene
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RNA(1)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT00000025029.12597nt
[+]
Expression
RNA-seq
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RPKM
Reference RNA: 
IMMRT10010029695 (chr14:16084677-16094182, 2614bps)
View:
Lab: 
Burge Charles Gilad2010 Gilad2011 JD Kaessmann Norgren Philipp RB Soojin Wang Yi
Sample: 
brain caudate nucleus cerebellum colon fat frontal cerebral cortex frontal pole heart
hippocampus kidney liver lung lymphoblastoid muscle orbital cerebral cortex spleen
testis thymus
RhesusBase IDLabIndividualSampleRPKM?RPKM Level Housekeeping GenesRB Score?More
RBNGS0120019 Burge C colon 58.55 (97.61)
546.43 (99.88) Full [+] 7.01 (74.74) [+]
RBNGS0120001 Burge A colon 43.44 (96.9)
426.94 (99.88) Full [+] 6.59 (57.22) [+]
RBNGS0120010 Burge B colon 39.73 (96.77)
433.31 (99.85) Full [+] 7.65 (86.6) [+]
RBNGS0120008 Burge A testis 36.25 (94.12)
237.29 (99.55) Full [+] 7.23 (80.93) [+]
RBNGS0120016 Burge B spleen 32.55 (96.53)
243.82 (99.72) Full [+] 7.32 (82.99) [+]
RBNGS0120023 Burge C lung 31.10 (95.73)
132.98 (99.35) Full [+] 7.14 (77.84) [+]
RBNGS0120025 Burge C spleen 30.55 (95.7)
134.12 (99.41) Full [+] 6.95 (73.71) [+]
RBNGS0120009 Burge B brain 29.90 (96.16)
593.73 (99.98) Full [+] 7.66 (88.14) [+]
RBNGS0120018 Burge C brain 28.10 (95.93)
601.19 (99.99) Full [+] 6.36 (52.06) [+]
RBNGS0120026 Burge C testis 24.72 (92.54)
123.59 (99.40) Full [+] 7.16 (78.87) [+]
RBNGS0120014 Burge B lung 24.57 (94.74)
169.19 (99.56) Full [+] 7.58 (84.02) [+]
RBNGS0120012 Burge B kidney 24.18 (93.85)
694.13 (99.93) Full [+] 7.59 (85.05) [+]
RBNGS0120000 Burge A brain 24.07 (95.4)
552.62 (99.98) Full [+] 6.68 (60.31) [+]
RBNGS0120007 Burge A spleen 22.82 (94.35)
152.34 (99.53) Full [+] 6.81 (65.98) [+]
RBNGS0120005 Burge A lung 19.86 (93.4)
85.86 (99.12) Full [+] 6.92 (71.65) [+]
RBNGS0120021 Burge C kidney 19.84 (93.02)
208.26 (99.76) Full [+] 6.88 (70.1) [+]
RBNGS0120017 Burge B testis 17.97 (90.45)
105.21 (99.15) Full [+] 7.69 (89.18) [+]
RBNGS0120022 Burge C liver 16.01 (93.59)
252.91 (99.55) Full [+] 7.1 (76.8) [+]
RBNGS0120003 Burge A kidney 15.87 (90.68)
522.74 (99.88) Full [+] 5.97 (40.72) [+]
RBNGS0120013 Burge B liver 15.55 (93.96)
370.40 (99.71) Full [+] 7.78 (90.21) [+]
RBNGS0120004 Burge A liver 15.40 (92.75)
367.17 (99.72) Full [+] 7.07 (75.77) [+]
RBNGS0120011 Burge B heart 14.56 (93.39)
7151.00 (99.98) Full [+] 7.65 (86.6) [+]
RBNGS0120024 Burge C muscle 10.78 (91.72)
3166.11 (99.96) Full [+] 6.78 (64.43) [+]
RBNGS0120020 Burge C heart 10.71 (91.86)
559.13 (99.91) Full [+] 5.48 (20.62) [+]
RBNGS0120006 Burge A muscle 9.95 (92.61)
10528.36 (99.98) Full [+] 6.54 (54.12) [+]
RBNGS0120002 Burge A heart 8.76 (90.62)
814.11 (99.94) Full [+] 5.48 (20.62) [+]
RBNGS0120015 Burge B muscle 8.41 (90.05)
869.75 (99.94) Full [+] 6.18 (45.88) [+]
RBNGS0120030 Charles 256-95 lymphoblastoid 114.49 (98.19)
3288.60 (99.98) Full [+] 5.81 (32.47) [+]
RBNGS0120029 Charles 173-02 lymphoblastoid 114.44 (98.7)
3034.59 (99.99) Full [+] 5.81 (32.47) [+]
RBNGS0120027 Charles 150-99 lymphoblastoid 111.10 (98.44)
3590.65 (99.99) Full [+] 5.9 (37.63) [+]
RBNGS0120032 Charles 303-97 lymphoblastoid 110.19 (98.57)
3680.10 (100.00) Full [+] 5.92 (38.66) [+]
RBNGS0120031 Charles 265-95 lymphoblastoid 104.85 (98.26)
4220.63 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120028 Charles 153-99 lymphoblastoid 76.81 (97.38)
4927.60 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120033 Gilad2010 female1 liver 18.29 (93.06)
246.59 (99.52) Full [+] 5.67 (24.23) [+]
RBNGS0120038 Gilad2010 male3 liver 18.06 (92.28)
295.78 (99.68) Full [+] 5.77 (30.41) [+]
RBNGS0120035 Gilad2010 female3 liver 17.97 (91.77)
509.01 (99.75) Full [+] 5.71 (26.8) [+]
RBNGS0120036 Gilad2010 male1 liver 15.07 (91.82)
284.57 (99.59) Full [+] 5.74 (29.38) [+]
RBNGS0120034 Gilad2010 female2 liver 12.55 (90.34)
265.16 (99.54) Full [+] 5.58 (22.16) [+]
RBNGS0120037 Gilad2010 male2 liver 12.13 (90.96)
342.77 (99.68) Full [+] 5.13 (15.98) [+]
RBNGS0120039 Gilad2011 RNA R1 lymphoblastoid 232.88 (99.42)
2783.10 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120041 Gilad2011 RNA R3 lymphoblastoid 211.06 (99.34)
2868.12 (99.99) Full [+] 5.98 (43.3) [+]
RBNGS0120040 Gilad2011 RNA R2 lymphoblastoid 198.93 (99.22)
2909.34 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120042 JD mixtured frontal cerebral cortex 33.92 (94.06)
997.88 (99.99) Full [+] 6.08 (44.85) [+]
RBNGS0120043 Kaessmann female brain 34.46 (95.2)
1041.37 (99.99) Full [+] 5.88 (36.6) [+]
RBNGS0120044 Kaessmann female cerebellum 32.59 (96.23)
544.80 (99.97) Full [+] 5.61 (23.2) [+]
RBNGS0120049 Kaessmann male1 cerebellum 32.50 (95.3)
647.87 (99.97) Full [+] 5.71 (26.8) [+]
RBNGS0120055 Kaessmann male2 testis 30.34 (92.22)
73.01 (97.21) Full [+] 7.29 (81.96) [+]
RBNGS0120048 Kaessmann male1 brain 27.95 (92.89)
1215.60 (99.99) Full [+] 7.17 (79.9) [+]
RBNGS0120054 Kaessmann male2 brain 27.09 (94.18)
798.21 (99.99) Full [+] 5.23 (17.01) [+]
RBNGS0120051 Kaessmann male1 kidney 19.98 (93.43)
711.25 (99.96) Full [+] 4.07 (13.92) [+]
RBNGS0120046 Kaessmann female kidney 19.10 (90.14)
1081.82 (99.97) Full [+] 5.72 (28.35) [+]
RBNGS0120053 Kaessmann male1 testis 17.51 (87.92)
79.24 (97.96) Full [+] 5.81 (32.47) [+]
RBNGS0120050 Kaessmann male1 heart 16.34 (90.54)
599.06 (99.87) Full [+] 5.32 (19.07) [+]
RBNGS0120047 Kaessmann female liver 13.79 (91.02)
600.89 (99.75) Full [+] 6.19 (46.91) [+]
RBNGS0120045 Kaessmann female heart 11.76 (90.4)
764.28 (99.91) Full [+] 5.25 (18.04) [+]
RBNGS0120052 Kaessmann male1 liver 11.49 (88.51)
1067.66 (99.83) Full [+] 6.77 (63.4) [+]
RBNGS0120059 Norgren 001T NHP thymus 81.09 (97.93)
898.83 (99.94) Full [+] 6.88 (70.1) [+]
RBNGS0120058 Norgren 001T NHP testis 63.78 (97.2)
361.93 (99.82) Full [+] 6.63 (58.76) [+]
RBNGS0120057 Norgren 001T NHP orbital cerebral cortex 62.14 (96.97)
465.11 (99.89) Full [+] 6.72 (61.34) [+]
RBNGS0120065 Norgren BF23764 frontal cerebral cortex 44.72 (96.1)
639.64 (99.96) Full [+] 6.32 (50.0) [+]
RBNGS0120061 Norgren BF20336 frontal cerebral cortex 44.71 (95.82)
893.81 (99.99) Full [+] 6.85 (68.56) [+]
RBNGS0120066 Norgren BF23773 frontal cerebral cortex 43.17 (95.88)
780.30 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120064 Norgren BF23762 frontal cerebral cortex 42.79 (95.78)
703.56 (99.97) Full [+] 6.35 (51.03) [+]
RBNGS0120062 Norgren BF21178 frontal cerebral cortex 40.95 (95.39)
975.49 (99.99) Full [+] 6.81 (65.98) [+]
RBNGS0120060 Norgren 002T NHP caudate nucleus 29.92 (93.08)
913.62 (99.97) Full [+] 6.93 (72.68) [+]
RBNGS0120063 Norgren BF22215 frontal cerebral cortex 28.22 (92.47)
888.73 (99.97) Full [+] 6.63 (58.76) [+]
RBNGS0120056 Norgren 001T NHP caudate nucleus 25.42 (92.08)
634.09 (99.93) Full [+] 6.83 (67.53) [+]
RBNGS0120067 Philipp individual brain 3.07 (76.88)
126.37 (99.90) Full [+] 2.33 (9.79) [+]
RBNGS0120077 RB 0605151 testis 15.07 (89.52)
267.33 (99.88) Full [+] 8.59 (94.85) [+]
RBNGS0120076 RB 0605151 spleen 14.26 (88.71)
255.19 (99.72) Full [+] 8.62 (96.39) [+]
RBNGS0120074 RB 0605151 lung 11.77 (87.28)
256.42 (99.77) Full [+] 8.67 (97.42) [+]
RBNGS0120069 RB 0605151 cerebellum 11.04 (89.74)
705.06 (99.99) Full [+] 7.86 (91.75) [+]
RBNGS0120070 RB 0605151 fat 10.66 (87.65)
208.39 (99.62) Full [+] 8.59 (94.85) [+]
RBNGS0120075 RB 0605151 muscle 10.46 (89.77)
4525.95 (99.98) Full [+] 8.76 (99.48) [+]
RBNGS0120068 RB 0605151 brain 10.04 (87.45)
910.13 (99.99) Full [+] 8.23 (93.3) [+]
RBNGS0120073 RB 0605151 liver 7.07 (86.38)
412.47 (99.69) Full [+] 8.75 (98.45) [+]
RBNGS0120072 RB 0605151 kidney 7.02 (83.94)
574.03 (99.91) Full [+] 7.86 (91.75) [+]
RBNGS0120071 RB 0605151 heart 3.29 (82.48)
654.26 (99.90) Full [+] 6.75 (62.37) [+]
RBNGS0120088 Soojin Y04-21 frontal pole 0.74 (88.35)
0.00 (31.03) Full [+] 2.5 (11.86) [+]
RBNGS0120078 Soojin Y04-03 caudate nucleus 0.00 (49.34)
0.00 (49.34) Full [+] 1.77 (2.58) [+]
RBNGS0120079 Soojin Y04-03 frontal pole 0.00 (31.36)
0.00 (31.36) Full [+] 2.45 (10.82) [+]
RBNGS0120080 Soojin Y04-03 hippocampus 0.00 (49.36)
0.00 (49.36) Full [+] 1.88 (5.67) [+]
RBNGS0120081 Soojin Y04-05 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.68 (1.55) [+]
RBNGS0120082 Soojin Y04-05 frontal pole 0.00 (45.92)
0.00 (45.92) Full [+] 3.36 (12.89) [+]
RBNGS0120083 Soojin Y04-05 hippocampus 0.00 (49.5)
0.00 (49.50) Full [+] 1.9 (6.7) [+]
RBNGS0120084 Soojin Y04-20 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.54 (0.52) [+]
RBNGS0120085 Soojin Y04-20 frontal pole 0.00 (49.78)
0.00 (49.78) Full [+] 2.1 (8.76) [+]
RBNGS0120086 Soojin Y04-20 hippocampus 0.00 (49.74)
0.00 (49.74) Full [+] 1.94 (7.73) [+]
RBNGS0120087 Soojin Y04-21 caudate nucleus 0.00 (49.4)
0.00 (49.40) Full [+] 1.81 (3.61) [+]
RBNGS0120089 Soojin Y04-21 hippocampus 0.00 (49.46)
0.00 (49.46) Full [+] 1.84 (4.64) [+]
RBNGS0120090 Wang individual brain 24.21 (92.06)
917.80 (99.99) Full [+] 6.28 (48.97) [+]
RBNGS0120092 Wang individual kidney 22.81 (90.46)
1393.19 (99.97) Full [+] 6.2 (47.94) [+]
RBNGS0120095 Wang individual testis 18.04 (87.11)
118.24 (98.89) Full [+] 6.42 (53.09) [+]
RBNGS0120093 Wang individual liver 12.43 (91.0)
338.16 (99.64) Full [+] 5.98 (43.3) [+]
RBNGS0120094 Wang individual muscle 8.55 (87.19)
5119.89 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120091 Wang individual heart 5.78 (84.23)
912.82 (99.92) Full [+] 4.78 (14.95) [+]
RBNGS0120096 Yi individual cerebellum 29.53 (94.38)
520.64 (99.96) Full [+] 5.7 (25.26) [+]
RPKM Comparison
Human 
Macaque 
Mouse 
23.93
 
23.21
 
29.93
 
38.80
 
26.41
 
33.55
 
15.79
 
10.17
 
18.81
 
28.82
 
18.40
 
25.49
 
60.46
 
27.96
 
39.94
 
brain cerebellum heart kidney testis
Percentile Rank Comparison
Human 
Macaque 
Mouse 
91.33
 
91.79
 
92.82
 
94.82
 
93.91
 
93.50
 
89.63
 
89.07
 
90.22
 
92.45
 
90.79
 
91.14
 
96.07
 
91.39
 
92.59
 
brain cerebellum heart kidney testis
Relative RPKM Comparison
Human 
Macaque 
Mouse 
0.034
 
0.032
 
N.A
 
0.048
 
0.046
 
N.A
 
0.017
 
0.012
 
N.A
 
0.039
 
0.034
 
N.A
 
0.120
 
0.193
 
N.A
 
brain cerebellum heart kidney testis