For each macaque gene, we provided a Gene Page here to illustrate detailed functional annotations in different categories, such as gene information, expression profile, regulation, variation and repeats, phenotypes and disease, function, as well as drug development.

Summary
Entrez ID: 699096 (Human: 10402)
Offical Symbol: ST3GAL6 (Human: ST3GAL6)
Strand: +
Location: chr2:18932571-18989819
Gene Biotype: protein-coding
Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Alias: N.A.
RefSeq: (NW_001112540.1, XM_001089053.2, XP_001089053.2) (NC_007859.1, XM_001089053.2, XP_001089053.2)
Ensembl: (ENSMMUG00000017436, ENSMMUT00000024520, ENSMMUP00000022952)
UniGene: Mmu.24301
UniProt: F6YSL0 (F6YSL0_MACMU)
Publications: N.A.
Wiki: Wikipedia, WikiGenes, GeneCard
RefSeq Summary:

The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]. Refer to NM_001271142.

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Structure
RefSeq
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RNA(1)
>gi|297284851|ref|XM_001089053.2| PREDICTED: Macaca mulatta ST3 beta-galactoside alpha-2,3-sialyltransferase 6, transcript variant 1 (ST3GAL6), mRNA1905nt Get Sequence
[+]
Protein(1)
>gi|297284852|ref|XP_001089053.2| PREDICTED: type 2 lactosamine alpha-2,3-sialyltransferase isoform 1 [Macaca mulatta]392AA Get Sequence
[+]
Ensembl
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RNA(1)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT000000245201908nt
[+]
RhesusBase2 Gene
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RNA(1)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT000000245201908nt
[+]
Expression
RNA-seq
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RPKM
Reference RNA: 
IMMRT10011004797 (chr2:18932076-18991227, 3296bps)
View:
Lab: 
Burge Charles Gilad2010 Gilad2011 JD Kaessmann Norgren Philipp RB Soojin Wang Yi
Sample: 
brain caudate nucleus cerebellum colon fat frontal cerebral cortex frontal pole heart
hippocampus kidney liver lung lymphoblastoid muscle orbital cerebral cortex spleen
testis thymus
RhesusBase IDLabIndividualSampleRPKM?RPKM Level Housekeeping GenesRB Score?More
RBNGS0120013 Burge B liver 24.58 (96.05)
370.40 (99.71) Full [+] 7.78 (90.21) [+]
RBNGS0120022 Burge C liver 18.79 (94.47)
252.91 (99.55) Full [+] 7.1 (76.8) [+]
RBNGS0120021 Burge C kidney 16.91 (91.78)
208.26 (99.76) Full [+] 6.88 (70.1) [+]
RBNGS0120000 Burge A brain 16.82 (92.77)
552.62 (99.98) Full [+] 6.68 (60.31) [+]
RBNGS0120004 Burge A liver 13.46 (91.77)
367.17 (99.72) Full [+] 7.07 (75.77) [+]
RBNGS0120009 Burge B brain 13.41 (89.76)
593.73 (99.98) Full [+] 7.66 (88.14) [+]
RBNGS0120018 Burge C brain 11.73 (89.0)
601.19 (99.99) Full [+] 6.36 (52.06) [+]
RBNGS0120011 Burge B heart 9.64 (90.79)
7151.00 (99.98) Full [+] 7.65 (86.6) [+]
RBNGS0120012 Burge B kidney 7.11 (82.13)
694.13 (99.93) Full [+] 7.59 (85.05) [+]
RBNGS0120024 Burge C muscle 6.72 (88.09)
3166.11 (99.96) Full [+] 6.78 (64.43) [+]
RBNGS0120003 Burge A kidney 6.64 (81.79)
522.74 (99.88) Full [+] 5.97 (40.72) [+]
RBNGS0120016 Burge B spleen 3.87 (72.73)
243.82 (99.72) Full [+] 7.32 (82.99) [+]
RBNGS0120005 Burge A lung 3.86 (72.49)
85.86 (99.12) Full [+] 6.92 (71.65) [+]
RBNGS0120014 Burge B lung 3.49 (72.17)
169.19 (99.56) Full [+] 7.58 (84.02) [+]
RBNGS0120026 Burge C testis 3.23 (66.06)
123.59 (99.40) Full [+] 7.16 (78.87) [+]
RBNGS0120023 Burge C lung 3.03 (68.49)
132.98 (99.35) Full [+] 7.14 (77.84) [+]
RBNGS0120007 Burge A spleen 3.00 (69.52)
152.34 (99.53) Full [+] 6.81 (65.98) [+]
RBNGS0120015 Burge B muscle 2.21 (75.9)
869.75 (99.94) Full [+] 6.18 (45.88) [+]
RBNGS0120017 Burge B testis 2.06 (63.83)
105.21 (99.15) Full [+] 7.69 (89.18) [+]
RBNGS0120008 Burge A testis 1.01 (55.3)
237.29 (99.55) Full [+] 7.23 (80.93) [+]
RBNGS0120025 Burge C spleen 1.01 (59.71)
134.12 (99.41) Full [+] 6.95 (73.71) [+]
RBNGS0120002 Burge A heart 0.94 (67.75)
814.11 (99.94) Full [+] 5.48 (20.62) [+]
RBNGS0120006 Burge A muscle 0.89 (76.39)
10528.36 (99.98) Full [+] 6.54 (54.12) [+]
RBNGS0120010 Burge B colon 0.61 (57.41)
433.31 (99.85) Full [+] 7.65 (86.6) [+]
RBNGS0120020 Burge C heart 0.60 (63.61)
559.13 (99.91) Full [+] 5.48 (20.62) [+]
RBNGS0120019 Burge C colon 0.46 (54.81)
546.43 (99.88) Full [+] 7.01 (74.74) [+]
RBNGS0120001 Burge A colon 0.45 (54.66)
426.94 (99.88) Full [+] 6.59 (57.22) [+]
RBNGS0120028 Charles 153-99 lymphoblastoid 2.07 (69.11)
4927.60 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120027 Charles 150-99 lymphoblastoid 0.48 (57.22)
3590.65 (99.99) Full [+] 5.9 (37.63) [+]
RBNGS0120031 Charles 265-95 lymphoblastoid 0.12 (52.09)
4220.63 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120030 Charles 256-95 lymphoblastoid 0.12 (52.15)
3288.60 (99.98) Full [+] 5.81 (32.47) [+]
RBNGS0120032 Charles 303-97 lymphoblastoid 0.11 (51.72)
3680.10 (100.00) Full [+] 5.92 (38.66) [+]
RBNGS0120029 Charles 173-02 lymphoblastoid 0.03 (47.86)
3034.59 (99.99) Full [+] 5.81 (32.47) [+]
RBNGS0120037 Gilad2010 male2 liver 18.50 (93.79)
342.77 (99.68) Full [+] 5.13 (15.98) [+]
RBNGS0120034 Gilad2010 female2 liver 16.77 (92.62)
265.16 (99.54) Full [+] 5.58 (22.16) [+]
RBNGS0120038 Gilad2010 male3 liver 14.36 (90.35)
295.78 (99.68) Full [+] 5.77 (30.41) [+]
RBNGS0120036 Gilad2010 male1 liver 8.65 (86.34)
284.57 (99.59) Full [+] 5.74 (29.38) [+]
RBNGS0120035 Gilad2010 female3 liver 8.00 (83.23)
509.01 (99.75) Full [+] 5.71 (26.8) [+]
RBNGS0120033 Gilad2010 female1 liver 7.62 (84.27)
246.59 (99.52) Full [+] 5.67 (24.23) [+]
RBNGS0120041 Gilad2011 RNA R3 lymphoblastoid 0.03 (48.88)
2868.12 (99.99) Full [+] 5.98 (43.3) [+]
RBNGS0120039 Gilad2011 RNA R1 lymphoblastoid 0.00 (24.3)
2783.10 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120040 Gilad2011 RNA R2 lymphoblastoid 0.00 (24.26)
2909.34 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120042 JD mixtured frontal cerebral cortex 5.72 (71.15)
997.88 (99.99) Full [+] 6.08 (44.85) [+]
RBNGS0120046 Kaessmann female kidney 6.26 (75.32)
1081.82 (99.97) Full [+] 5.72 (28.35) [+]
RBNGS0120054 Kaessmann male2 brain 6.08 (74.96)
798.21 (99.99) Full [+] 5.23 (17.01) [+]
RBNGS0120043 Kaessmann female brain 5.52 (73.15)
1041.37 (99.99) Full [+] 5.88 (36.6) [+]
RBNGS0120048 Kaessmann male1 brain 5.39 (72.26)
1215.60 (99.99) Full [+] 7.17 (79.9) [+]
RBNGS0120049 Kaessmann male1 cerebellum 5.27 (72.28)
647.87 (99.97) Full [+] 5.71 (26.8) [+]
RBNGS0120052 Kaessmann male1 liver 4.57 (80.07)
1067.66 (99.83) Full [+] 6.77 (63.4) [+]
RBNGS0120047 Kaessmann female liver 4.42 (78.75)
600.89 (99.75) Full [+] 6.19 (46.91) [+]
RBNGS0120044 Kaessmann female cerebellum 4.32 (70.04)
544.80 (99.97) Full [+] 5.61 (23.2) [+]
RBNGS0120051 Kaessmann male1 kidney 3.48 (71.06)
711.25 (99.96) Full [+] 4.07 (13.92) [+]
RBNGS0120050 Kaessmann male1 heart 2.95 (67.85)
599.06 (99.87) Full [+] 5.32 (19.07) [+]
RBNGS0120045 Kaessmann female heart 1.46 (65.18)
764.28 (99.91) Full [+] 5.25 (18.04) [+]
RBNGS0120055 Kaessmann male2 testis 1.17 (56.12)
73.01 (97.21) Full [+] 7.29 (81.96) [+]
RBNGS0120053 Kaessmann male1 testis 1.04 (52.69)
79.24 (97.96) Full [+] 5.81 (32.47) [+]
RBNGS0120059 Norgren 001T NHP thymus 20.92 (88.68)
898.83 (99.94) Full [+] 6.88 (70.1) [+]
RBNGS0120056 Norgren 001T NHP caudate nucleus 13.65 (85.77)
634.09 (99.93) Full [+] 6.83 (67.53) [+]
RBNGS0120060 Norgren 002T NHP caudate nucleus 12.51 (84.0)
913.62 (99.97) Full [+] 6.93 (72.68) [+]
RBNGS0120061 Norgren BF20336 frontal cerebral cortex 5.81 (73.76)
893.81 (99.99) Full [+] 6.85 (68.56) [+]
RBNGS0120066 Norgren BF23773 frontal cerebral cortex 5.28 (72.59)
780.30 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120064 Norgren BF23762 frontal cerebral cortex 5.11 (71.93)
703.56 (99.97) Full [+] 6.35 (51.03) [+]
RBNGS0120065 Norgren BF23764 frontal cerebral cortex 5.01 (71.7)
639.64 (99.96) Full [+] 6.32 (50.0) [+]
RBNGS0120062 Norgren BF21178 frontal cerebral cortex 4.94 (71.89)
975.49 (99.99) Full [+] 6.81 (65.98) [+]
RBNGS0120063 Norgren BF22215 frontal cerebral cortex 4.03 (70.32)
888.73 (99.97) Full [+] 6.63 (58.76) [+]
RBNGS0120057 Norgren 001T NHP orbital cerebral cortex 0.49 (54.03)
465.11 (99.89) Full [+] 6.72 (61.34) [+]
RBNGS0120058 Norgren 001T NHP testis 0.44 (52.96)
361.93 (99.82) Full [+] 6.63 (58.76) [+]
RBNGS0120067 Philipp individual brain 3.32 (78.16)
126.37 (99.90) Full [+] 2.33 (9.79) [+]
RBNGS0120073 RB 0605151 liver 9.43 (89.0)
412.47 (99.69) Full [+] 8.75 (98.45) [+]
RBNGS0120075 RB 0605151 muscle 6.22 (84.39)
4525.95 (99.98) Full [+] 8.76 (99.48) [+]
RBNGS0120072 RB 0605151 kidney 5.68 (80.92)
574.03 (99.91) Full [+] 7.86 (91.75) [+]
RBNGS0120068 RB 0605151 brain 4.85 (77.52)
910.13 (99.99) Full [+] 8.23 (93.3) [+]
RBNGS0120069 RB 0605151 cerebellum 4.37 (77.96)
705.06 (99.99) Full [+] 7.86 (91.75) [+]
RBNGS0120074 RB 0605151 lung 2.61 (64.49)
256.42 (99.77) Full [+] 8.67 (97.42) [+]
RBNGS0120070 RB 0605151 fat 2.56 (68.66)
208.39 (99.62) Full [+] 8.59 (94.85) [+]
RBNGS0120076 RB 0605151 spleen 2.29 (63.3)
255.19 (99.72) Full [+] 8.62 (96.39) [+]
RBNGS0120077 RB 0605151 testis 1.65 (56.61)
267.33 (99.88) Full [+] 8.59 (94.85) [+]
RBNGS0120071 RB 0605151 heart 1.46 (72.45)
654.26 (99.90) Full [+] 6.75 (62.37) [+]
RBNGS0120079 Soojin Y04-03 frontal pole 28.78 (99.23)
0.00 (31.36) Full [+] 2.45 (10.82) [+]
RBNGS0120088 Soojin Y04-21 frontal pole 23.15 (99.04)
0.00 (31.03) Full [+] 2.5 (11.86) [+]
RBNGS0120078 Soojin Y04-03 caudate nucleus 0.00 (49.34)
0.00 (49.34) Full [+] 1.77 (2.58) [+]
RBNGS0120080 Soojin Y04-03 hippocampus 0.00 (49.36)
0.00 (49.36) Full [+] 1.88 (5.67) [+]
RBNGS0120081 Soojin Y04-05 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.68 (1.55) [+]
RBNGS0120082 Soojin Y04-05 frontal pole 0.00 (45.92)
0.00 (45.92) Full [+] 3.36 (12.89) [+]
RBNGS0120083 Soojin Y04-05 hippocampus 0.00 (49.5)
0.00 (49.50) Full [+] 1.9 (6.7) [+]
RBNGS0120084 Soojin Y04-20 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.54 (0.52) [+]
RBNGS0120085 Soojin Y04-20 frontal pole 0.00 (49.78)
0.00 (49.78) Full [+] 2.1 (8.76) [+]
RBNGS0120086 Soojin Y04-20 hippocampus 0.00 (49.74)
0.00 (49.74) Full [+] 1.94 (7.73) [+]
RBNGS0120087 Soojin Y04-21 caudate nucleus 0.00 (49.4)
0.00 (49.40) Full [+] 1.81 (3.61) [+]
RBNGS0120089 Soojin Y04-21 hippocampus 0.00 (49.46)
0.00 (49.46) Full [+] 1.84 (4.64) [+]
RBNGS0120093 Wang individual liver 19.51 (94.16)
338.16 (99.64) Full [+] 5.98 (43.3) [+]
RBNGS0120094 Wang individual muscle 17.71 (92.79)
5119.89 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120090 Wang individual brain 10.34 (81.78)
917.80 (99.99) Full [+] 6.28 (48.97) [+]
RBNGS0120092 Wang individual kidney 7.63 (78.37)
1393.19 (99.97) Full [+] 6.2 (47.94) [+]
RBNGS0120095 Wang individual testis 2.61 (61.66)
118.24 (98.89) Full [+] 6.42 (53.09) [+]
RBNGS0120091 Wang individual heart 2.21 (72.22)
912.82 (99.92) Full [+] 4.78 (14.95) [+]
RBNGS0120096 Yi individual cerebellum 6.82 (75.44)
520.64 (99.96) Full [+] 5.7 (25.26) [+]
RPKM Comparison
Human 
Macaque 
Mouse 
2.91
 
8.61
 
3.76
 
2.43
 
5.20
 
4.98
 
6.85
 
2.75
 
9.21
 
4.88
 
7.67
 
7.50
 
1.04
 
1.65
 
2.65
 
brain cerebellum heart kidney testis
Percentile Rank Comparison
Human 
Macaque 
Mouse 
60.44
 
81.04
 
60.42
 
60.25
 
73.93
 
65.10
 
79.75
 
71.41
 
80.55
 
68.45
 
80.20
 
74.26
 
36.19
 
58.15
 
58.27
 
brain cerebellum heart kidney testis
Relative RPKM Comparison
Human 
Macaque 
Mouse 
0.005
 
0.015
 
N.A
 
0.003
 
0.009
 
N.A
 
0.009
 
0.002
 
N.A
 
0.009
 
0.019
 
N.A
 
0.002
 
0.014
 
N.A
 
brain cerebellum heart kidney testis